Login
Language: English  |  中文 
 
 
 

广西民族大学机构知识库 > → 广西民族大学 > → 化学化工学院 > → 期刊论文 >


Please use this identifier to cite or link to this item: http://ir.calis.edu.cn/hdl/530500/17573

Title: 南海红树林内生真菌ZZF42中生物碱类代谢产物的研究
Other Titles: Alkaloid Metabolites of Mangrove Endophytic Fungus ZZF42 from the South China Sea
Authors: 中山大学化学与化学工程学院
广西民族大学化学与生态工程学院
广西师范大学化学与化学工程学院
黄忠京
郭志勇
杨瑞云
佘志刚
林永成
Keywords: 红树林内生真菌
代谢产物
生物碱
Issue Date: 2007-08-25
Publisher: 中药材
Citation: 中药材,2007,08:939-941
Abstract: 从南海红树林内生真菌ZZF42的代谢产物中分离得到4种生物碱:Apicidin(1),N-methylharman(2),环苯丙-酪肽(3),吲哚-3-乙酸(4)。它们的结构通过波谱方法得到确定。化合物1为首次从该海洋真菌中分离发现,化合物2为首次从该海洋微生物中分离发现。药理实验结果表明,化合物1对人鼻咽癌细胞株KB和人鼻咽癌细胞耐药株KBv200的IC50均小于0.78μg/ml。Four compounds, apicidin( 1 ) , N-methylharman( 2 ) , cylo (Phe-Tyr) ( 3 ) and indole-3-acetic acid (4) were isolated from the mangrove endophytic fungus ZZF42 from the South China Sea. Their structures were elucidated by spectral data. Compound 1 was first isolated from the marine fungus. Compound 2 was firstly isolated from marine microorganism. Compound 1 exhibited selective in vitro cytotoxicity towards KB and KBv200 with ICs0 values of less than 0. 78μg/ml.
URI: http://ir.calis.edu.cn/hdl/530500/17573
Appears in Collections:期刊论文

Files in This Item:

File Description SizeFormat
南海红树林内生真菌ZZF42中生物碱类代谢产物的研究_黄忠京.pdf160.58 kBAdobe PDFView/Open
Recommend this item     Add this item as favorite
View Statistics

License: See CALIS IR operational policies.

Number of Online Users: 86     Total of Site Visit: 4511336